The sayaph1 Diaries
The sayaph1 Diaries
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Beberapa dari mereka yang melakukan protes adalah pengikut menteri keamanan garis keras Israel, Itamar Ben Gvir, orang yang bertanggung jawab atas layanan penjara.
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Organisasi hak asasi manusia terkemuka di Israel mengatakan puluhan tahanan Palestina yang ditahan di penjara Israel mengalami penyiksaan dan kondisi mereka semakin memburuk sejak pertikaian tak berkesudahan di Gaza sejak Oktober 2023.
Hamas menerima ucapan selamat dari kelompok-kelompok Palestina karena memilih Yahya Sinwar sebagai pemimpinnya, termasuk Fatah yang telah lama berseteru dengan kelompok tersebut.
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Perjuangan seorang pria selama 35 tahun mencari keadilan atas pembunuhan adiknya oleh geng homofobik di Australia
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In this research, we recognized Aph1 mutations which can be Lively from the absence of nicastrin (NCT) employing a yeast γ-secretase assay. We analyzed these Aph1 mutations from the existence of NCT; we observed that the L30F/T164A mutation is activating. When launched in mouse embryonic fibroblasts, the mutation enhanced cleavage. The Aph1 mutants made much more short and extended Aβs than did the wild-variety Aph1, without the need of an apparent modulatory operate. The mutants did not transform the amount of γ-secretase intricate, suggesting that L30F/T164A boosts catalytic action. Our effects supply insights in to the regulatory perform of Aph1 in γ-secretase exercise.
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